This is an image of murine CTLA4 (CD152) which is necessary for inhibiting the T cells. It binds to CD28 with a higher affinity than the costimulatory molecules CD80 and CD86. This image is derived from Protein Data Bank data 1DQT which was published by Ostrov et al. in 2000. I rendered the image in PyMol myself based on the published pdb file.

For the published pdb, please see: Ostrov, D.A., Shi, W., Schwartz, J.C., Almo, S.C., Nathenson, S.G. Structure of murine CTLA-4 and its role in modulating T cell responsiveness. Science v290 pp.816-819 , 2000.

描述CTLA4 Crystal Structure.rsh.png	Crystal structure of CTLA4 as published in the Protein Data Bank (PDB: 1DQT)
日期	2006年10月12日
来源	Created from PDB 1DQT and rendered by me using Pymol
作者	Ramin Herati
授权 (二次使用本文件)	Public domainPublic domainfalsefalse 我，本作品著作权人，释出本作品至公有领域。这适用于全世界。 在一些国家这可能不合法；如果是这样的话，那么： 我无条件地授予任何人以任何目的使用本作品的权利，除非这些条件是法律规定所必需的。