Template:PBB/2034

Endothelial PAS domain protein 1 内皮PAS结构域蛋白-1
PDB rendering based on 1p97.
有效结构 PDB 直系同源检索：PDBe, RCSB PDB查询代码列表 1P97, 2A24, 3F1N, 3F1O, 3F1P, 3H7W, 3H82, 4GHI, 4GS9
标识
代号	EPAS1; ECYT4; HIF2A; HLF; MOP2; PASD2; bHLHe73
扩展标识	遗传学：603349 鼠基因：109169 同源基因：1095 ChEMBL: 1744522 GeneCards: EPAS1 Gene
基因本体论描述 分子功能 · RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription · DNA binding · signal transducer activity · protein binding · transcription factor binding · histone acetyltransferase binding · sequence-specific DNA binding · protein heterodimerization activity 细胞成分 · nucleoplasm · transcription factor complex · cytosol 生物过程 · angiogenesis · response to hypoxia · embryonic placenta development · blood vessel remodeling · regulation of heart rate · transcription from RNA polymerase II promoter · mitochondrion organization · signal transduction · visual perception · erythrocyte differentiation · lung development · cellular response to stress · norepinephrine metabolic process · surfactant homeostasis · regulation of transcription from RNA polymerase II promoter in response to oxidative stress · positive regulation of transcription from RNA polymerase II promoter · cell maturation · myoblast fate commitment · regulation of transcription from RNA polymerase II promoter in response to hypoxia · cellular response to hypoxia Sources: Amigo / QuickGO
RNA表达模式
更多表达数据
直系同源体
物种	人类	小鼠
Entrez	2034	13819
Ensembl	ENSG00000116016	ENSMUSG00000024140
UniProt	Q99814	P97481
mRNA序列	NM_001430	NM_010137
蛋白序列	NP_001421	NP_034267
基因位置	Chr 2: 46.52 – 46.61 Mb	Chr 17: 86.75 – 86.83 Mb
PubMed查询	[1]	[2]