2-(异氰基甲硫基)苯甲醚
| 2-(异氰基甲硫基)苯甲醚 | |
|---|---|
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| IUPAC名 1-[(Isocyanomethyl)sulfanyl]-2-methoxybenzene | |
| 别名 | Asmic; Anisyl sulfanyl methyl isocyanide |
| 识别 | |
| CAS号 | 1803329-89-6  [ECHA]
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| PubChem | 123978413 |
| ChemSpider | 114826701 |
| SMILES |
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| 性质 | |
| 化学式 | C9H9NOS |
| 摩尔质量 | 179.24 g·mol−1 |
| 外观 | 灰白色固体 |
| 熔点 | 27 °C（300 K） |
| 溶解性（极性有机溶剂） | 可溶 |
| 危险性 | |
GHS危险性符号 
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| GHS提示词 | 警告 |
| H-术语 | H301, H311, H315, H319, H331, H335 |
| P-术语 | P261, P262, P264, P264+265, P270, P271, P280, P301+316, P302+352, P304+340, P305+351+338, P316, P319, P321 |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
2-(异氰基甲硫基)苯甲醚是一种有机化合物，化学式为C9H9NOS。[1][2]它可通过相应酰胺和磷酰氯的脱水反应制得[3][4]，它是无色至灰白色低熔点（27 °C）的固体。[5]它可以用于合成多取代异腈（R1R2R3CNC）。[3]
参考文献
[编辑]- ^ Fleming, F. F. Composition, Synthesis, and Use of Isonitriles. U.S. Patent 8,269,032, Sept 18, 2012.
- ^ Zhu, Jieping; Tron, Gian Cesare; Novellino, Ettore; Massarotti, Alberto; Mercalli, Valentina; Basso, Andrea; Giustiniano, Mariateresa. To each his own: isonitriles for all flavors. Functionalized isocyanides as valuable tools in organic synthesis. Chemical Society Reviews. 2017-03-06, 46 (5): 1295–1357. ISSN 1460-4744. PMID 27983738. doi:10.1039/C6CS00444J （英语）.
- ^ 3.0 3.1 Alwedi, Embarek; Lujan-Montelongo, J. Armando; Pitta, Bhaskar R.; Chao, Allen; Cortés-Mejía, Rodrigo; del Campo, Jorge M.; Fleming, Fraser F. Asmic: An Exceptional Building Block for Isocyanide Alkylations. Organic Letters. 2018-09-21, 20 (18): 5910–5913. PMC 6172042
. PMID 30188137. doi:10.1021/acs.orglett.8b02574.
- ^ Shenvi, Ryan A.; Schnermann, Martin J. Syntheses and biological studies of marine terpenoids derived from inorganic cyanide. Natural Product Reports. 2015-03-25, 32 (4): 543–577. PMC 4414506 . PMID 25514696. doi:10.1039/C4NP00109E （英语）.
- ^ Abstracts of Papers, 256th ACS National Meeting & Exposition, Boston, MA, United States, August 19-23, 2018 ASMIC-driven synthesis of vinyl isocyanide
