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帽柱木碱

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Mitragynine
临床资料
给药途径口服给药
药物类别英语Drug class鸦片
ATC码
  • 未分配
法律规范状态
法律规范
  • 受管控(S8)
  • 未列入管制
  • NpSG
  • NZ未列入管制
  • PSA
  • 未列入管制
  • UN未列入管制
  • In general legal for medical and research uses as a research chemical.[1]
药物动力学数据
生物利用度21%
代谢产物7-羟基帽柱碱
生物半衰期7–39 hours
识别信息
  • methyl (16E)-9,17-dimethoxy-16,17-didehydro-20β-corynan-16-carboxylate
CAS号4098-40-2
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C23H30N2O4
摩尔质量398.50 g·mol−1
3D模型(JSmol英语JSmol
熔点102–106 °C[3]
  • COC1=CC=CC2=C1C3=C([C@@](C[C@H](/C(C(OC)=O)=C\OC)[C@H](CC)C4)([H])N4CC3)N2
  • InChI=1S/C23H30N2O4/c1-5-14-12-25-10-9-15-21-18(7-6-8-20(21)28-3)24-22(15)19(25)11-16(14)17(13-27-2)23(26)29-4/h6-8,13-14,16,19,24H,5,9-12H2,1-4H3/b17-13+/t14-,16+,19+/m1/s1
  • Key:LELBFTMXCIIKKX-QVRQZEMUSA-N

帽柱木碱(英语:Mitragynine)是一种有机化合物,分子式C23H30N2O4,属于吲哚生物碱,存在于卡痛树Mitragyna speciosa)等植物中,用作精神药物[4]

参考文献

[编辑]
  1. ^ 指定薬物一覧 [List of designated drugs] (PDF). 障害福祉のお仕事の世界 (The world of disability welfare work). [5 December 2023] (Japanese). 
  2. ^ Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Diário Oficial da União. 2023-03-31 (2023-04-04) [2023-08-15]. (原始内容存档于2023-08-03) (巴西葡萄牙语). 
  3. ^ Kratom profile (chemistry, effects, other names, origin, mode of use, other names, medical use, control status). European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). 
  4. ^ Hassan Z, Muzaimi M, Navaratnam V, Yusoff NH, Suhaimi FW, Vadivelu R, Vicknasingam BK, Amato D, von Hörsten S, Ismail NI, Jayabalan N, Hazim AI, Mansor SM, Müller CP. From Kratom to mitragynine and its derivatives: physiological and behavioural effects related to use, abuse, and addiction. Neuroscience and Biobehavioral Reviews. February 2013, 37 (2): 138–151. PMID 23206666. S2CID 8463133. doi:10.1016/j.neubiorev.2012.11.012.