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醋酸左炔诺孕酮

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醋酸左炔诺孕酮
临床资料
其他名称LNG-A; LNGA; 3-Ketonorgestimate; Levonorgestrel 17β-acetate; D-(–)-Norgestrel 17β-acetate; 17α-Ethynyl-18-methylestr-4-en-17β-ol-3-one 17β-acetate; 17β-Acetoxy-13β-ethyl-17α-ethynylgon-4-en-3-one
药物类别英语Drug class孕激素
识别信息
  • [(8R,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] acetate
CAS号13732-69-9
18290-31-8)
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.123.252 编辑维基数据链接
化学信息
化学式C23H30O3
摩尔质量354.49 g·mol−1
3D模型(JSmol英语JSmol
  • CC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)OC(=O)C)CCC4=CC(=O)CC[C@H]34
  • InChI=1S/C23H30O3/c1-4-22-12-10-19-18-9-7-17(25)14-16(18)6-8-20(19)21(22)11-13-23(22,5-2)26-15(3)24/h2,14,18-21H,4,6-13H2,1,3H3/t18-,19+,20+,21-,22-,23-/m0/s1
  • Key:YDQDJLTYVZAOQX-GOMYTPFNSA-N

醋酸左炔诺孕酮(英语:Levonorgestrel acetate,缩写LNG-A,化学名:左炔诺孕酮-17β-乙酸酯levonorgestrel 17β-acetate),是一种有机化合物,分子式为C23H30O3,属于19-去甲孕酮孕激素,从未上市销售[1][2][3][4]

参考文献

[编辑]
  1. ^ Naderi S, Fotherby K. Long-acting contraceptive agents: in vitro hydrolysis of esters of norethisterone and levonorgestrel. Steroids. 1983, 41 (3): 397–417. PMID 6419410. S2CID 28094296. doi:10.1016/0039-128x(83)90110-1. 
  2. ^ Kuhl H. Pharmacology of estrogens and progestogens: influence of different routes of administration (PDF). Climacteric. 2005, 8 (Suppl 1): 3–63. PMID 16112947. S2CID 24616324. doi:10.1080/13697130500148875. 
  3. ^ Schindler AE, Campagnoli C, Druckmann R, Huber J, Pasqualini JR, Schweppe KW, Thijssen JH. Classification and pharmacology of progestins. Maturitas. 2008, 61 (1–2): 171–80. PMID 19434889. doi:10.1016/j.maturitas.2008.11.013. 
  4. ^ Alvarez-Sanchez F, Brache V, Jackanicz T, Faundes A. Evaluation of four different contraceptive vaginal rings: steroid serum levels, luteal activity, bleeding control and lipid profiles. Contraception. 1992, 46 (4): 387–98. PMID 1486777. doi:10.1016/0010-7824(92)90101-x.