普沙托韋

普沙托韋
臨床資料
商品名（英語：Drug nomenclature）	Presatovir
法律規範狀態
法律規範	美：Investigational New Drug;
識別資訊
	IUPAC命名法 N-[2-[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carbonyl]-4-chlorophenyl]methanesulfonamide; ;
CAS號	1353625-73-6
PubChem CID	58029842;
化學資訊
化學式	C24H30ClN7O3S
摩爾質量	532.1
3D模型（JSmol（英語：JSmol））	交互式圖像;
	SMILES CC1=CN2C(=CC(=N2)[C@@H]3CCCCN3C(=O)C4=C(C=CC(=C4)Cl)NS(=O)(=O)C)N=C1N5CC[C@@H](C5)N;
	InChI InChI=1S/C24H30ClN7O3S/c1-15-13-32-22(27-23(15)30-10-8-17(26)14-30)12-20(28-32)21-5-3-4-9-31(21)24(33)18-11-16(25)6-7-19(18)29-36(2,34)35/h6-7,11-13,17,21,29H,3-5,8-10,14,26H2,1-2H3/t17-,21-/m0/s1; Key:GOFXWTVKPWJNGD-UWJYYQICSA-N;

普沙托韋（GS-5806，化學式C₂₄H₃₀ClN₇O₃S）是一種抗病毒藥，被開發用於治療呼吸道合胞病毒感染。它作為一種融合抑制劑，在II期臨床試驗中顯示出較好的療效。^[1]^[2]

參見

^ Marty FM, Chemaly RF, Mullane KM, Lee DG, Hirsch HH, Small CB, et al. A Phase 2b, Randomized, Double-blind, Placebo-Controlled Multicenter Study Evaluating Antiviral Effects, Pharmacokinetics, Safety, and Tolerability of Presatovir in Hematopoietic Cell Transplant Recipients with Respiratory Syncytial Virus (RSV) Infection of the Lower Respiratory Tract. Clinical Infectious Diseases. December 2019. PMID 31915807. doi:10.1093/cid/ciz1167.
^ Stray K, Perron M, Porter DP, Anderson F, Lewis SA, Perry J, et al. Drug resistance assessment following administration of RSV fusion inhibitor presatovir to participants experimentally infected with respiratory syncytial virus. The Journal of Infectious Diseases. January 2020. PMID 31971597. doi:10.1093/infdis/jiaa028.