2-異氰基丙烷
外觀
2-異氰基丙烷 | |
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英文名 | 2-isocyanopropane |
別名 | 異丙基異氰化物 |
識別 | |
CAS號 | 598-45-8 |
SMILES |
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性質 | |
化學式 | C4H7N |
摩爾質量 | 69.11 g·mol−1 |
外觀 | 無色惡臭液體[1] |
沸點 | 85—87 °C(358—360 K)[2] |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
2-異氰基丙烷是一種有機化合物,化學式為C4H7N,它是異丁腈的同分異構體。它可由異丙胺和三氯甲烷在氫氧化鈉和季銨鹽的存在下在溶劑中反應得到[3],N-異丙基甲酰胺和三氯氧磷在三乙胺的存在下於二氯甲烷中反應,也可得到2-異氰基丙烷。[1]它可作為配體和金屬形成配合物。[4]
參考文獻
[編輯]- ^ 1.0 1.1 Lijie Wang, Jamie Ferguson, Fanlong Zeng. Palladium-catalyzed direct coupling of 2-vinylanilines and isocyanides: an efficient synthesis of 2-aminoquinolines. Organic & Biomolecular Chemistry. 2015, 13 (47): 11486–11491 [2021-04-07]. ISSN 1477-0520. doi:10.1039/C5OB01659B (英語).
- ^ Henry Feuer, Harry Rubinstein, Arnold T. Nielsen. Reaction of Alkyl Isocyanides with Ozone. A New Isocyanate Synthesis 1. The Journal of Organic Chemistry. 1958-08, 23 (8): 1107–1109 [2021-04-07]. ISSN 0022-3263. doi:10.1021/jo01102a005 (英語).
- ^ Debin Zeng, Yuying Ma, Rui Zhang, Quandeng Nie, Zhengjie Cui, Yaxin Wang, Luqing Shang, Zheng Yin. Synthesis and structure–activity relationship of α-keto amides as enterovirus 71 3C protease inhibitors. Bioorganic & Medicinal Chemistry Letters. 2016-04, 26 (7): 1762–1766 [2021-04-07]. doi:10.1016/j.bmcl.2016.02.039. (原始內容存檔於2018-06-23) (英語).
- ^ Belén Alvarez, M. Angeles Alvarez, M. Esther García, Daniel García-Vivó, Miguel A. Ruiz. C−C and C−N Couplings Following Hydride Addition on Isocyanide Cyclopolyenyl Dimolybdenum Complexes to Give Tethered Aldimine and Aminocarbene Derivatives. Chemistry - A European Journal. 2017-10-09, 23 (56): 14027–14038 [2021-04-07]. doi:10.1002/chem.201702998 (英語).