原儿茶酸乙酯
| 原儿茶酸乙酯[1] | |
|---|---|
| |
| IUPAC名 Ethyl 3,4-dihydroxybenzoate | |
| 别名 | 3,4-二羟基苯甲酸乙酯 EDHB |
| 识别 | |
| CAS号 | 3943-89-3 
|
| PubChem | 77547 |
| ChemSpider | 69954 |
| SMILES |
|
| InChI |
|
| InChIKey | KBPUBCVJHFXPOC-UHFFFAOYSA-N |
| EINECS | 223-529-0 |
| ChEBI | 132364 |
| 性质 | |
| 化学式 | C9H10O4 |
| 摩尔质量 | 182.17 g·mol−1 |
| 外观 | 白色或淡棕黄色晶体 |
| 气味 | 无臭或微弱的苯酚气味 |
| 熔点 | 132-135 °C（405-408 K） |
| 沸点 | 357-358 °C（630-631 K）（[2]） |
| 溶解性（水） | 不溶于水，可溶于乙醇 |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
原儿茶酸乙酯（英语：Ethyl protocatechuate）是原儿茶酸与乙醇形成的酯，分子式C9H10O4，可在花生的种皮中发现[3][4]，在葡萄酒中也有发现[5]。
原儿茶酸乙酯也是脯氨酸-4-羟化酶的抑制剂[6]，可用于保护心肌[7]。
参考文献
[编辑]- ^ Ethyl protocatechuate on FAO website[失效链接]
- ^ Ethyl protocatechuate on www.thegoodscentscompany.com
- ^ Huang, S. C.; Yen, G. C.; Chang, L. W.; Yen, W. J.; Duh, P. D. Identification of an Antioxidant, Ethyl Protocatechuate, in Peanut Seed Testa. Journal of Agricultural and Food Chemistry. 2003, 51 (8): 2380–2383. PMID 12670184. doi:10.1021/jf0210019.
- ^ Yen, W. J.; Chang, L. W.; Duh, P. D. Antioxidant activity of peanut seed testa and its antioxidative component, ethyl protocatechuate. LWT - Food Science and Technology. 2005, 38 (3): 193. doi:10.1016/j.lwt.2004.06.004.
- ^ Baderschneider, B.; Winterhalter, P. Isolation and Characterization of Novel Benzoates, Cinnamates, Flavonoids, and Lignans from Riesling Wine and Screening for Antioxidant Activity. Journal of Agricultural and Food Chemistry. 2001, 49 (6): 2788–2798. PMID 11409967. doi:10.1021/jf010396d.
- ^ Wang, J.; Buss, J. L.; Chen, G.; Ponka, P.; Pantopoulos, K. The prolyl 4-hydroxylase inhibitor ethyl-3,4-dihydroxybenzoate generates effective iron deficiency in cultured cells. FEBS Letters. 2002, 529 (2–3): 309–312. PMID 12372619. doi:10.1016/S0014-5793(02)03389-6.
- ^ Philipp, S.; Cui, L.; Ludolph, B.; Kelm, M.; Schulz, R.; Cohen, M. V.; Downey, J. M. Desferoxamine and ethyl-3,4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS. AJP: Heart and Circulatory Physiology. 2005, 290 (1): H450–H457. PMID 16155105. doi:10.1152/ajpheart.00472.2005.